Paving the Way for Biomedical Innovation

The Frederick National Laboratory meets the nation’s most urgent biomedical research needs and serves as a national and global resource for the scientific community. 

Cancer Research

‘Pan-KRAS’ drug aiming at KRAS-related cancers lacking targeted therapies now being tested in humans

Patients with intractable cancers driven by mutations of the KRAS oncogene have few available therapies. Yet, an...

Laboratory develops clinical assay for recurrent thyroid cancer

The CLIA Molecular Diagnostics Laboratory (CMDL) at the Frederick National Laboratory for Cancer Research (FNL) developed and...

Advancing global cervical cancer research: HPV Serology Laboratory completes eight-year mission

After nearly eight years of meticulous collaborative effort, the HPV Serology Laboratory at the Frederick National Laboratory...

Frederick National Laboratory teams help evaluate plant virus’ preclinical safety as cancer treatment

Researchers at the University of California San Diego, in collaboration with Frederick National Laboratory for Cancer...

Pioneering biophysicist, computational biologist elected to the National Academy of Sciences

Ruth Nussinov , Ph.D., who discovered that dynamic ensembles are the true workhorses of cellular function and who has...

ASCO oral presentation, posters to explore use of liquid biopsy in rare cancers

Biswajit Das, Ph.D., MoCha associate director, will present this study in an oral abstract session on Friday, May 30 at 4:45...

Valuable medical and biological images languish for want of support

Experts are working globally on standards for sharing medical and biological image data, much of which cannot be reused...
What is this?

Image of a distal mouse femur with mineralization scored via random forest classification using HALO image analysis software. The Molecular Histopathology Laboratory investigates treatments for cancer and infectious diseases within the Laboratory Animal Sciences Program by providing support for tissue-based research in understanding disease mechanisms, integrating research and diagnostic activities, and characterizing multiple mouse models of cancer.

Information
Initiative

RAS Initiative

The RAS Initiative mobilizes the cancer research community to develop ways to treat cancers driven by the mutant RAS gene in an open model of collaboration among government, academic, and industry researchers.
220,000
People per year in the U.S. are diagnosed with cancers caused by KRAS mutations.
What is this? Surface representation of the structure of an oncogenic mutant of KRAS in complex with RAS-binding domains of RAF1 Kinase. The GMPPNP bound to oncogenic KRAS mutant is shown in ball-and-stick representation.
Information
Initiative

Center for Innovation and Strategic Partnerships

We bring the Frederick National Laboratory’s distinct capabilities to the broader research community to help solve urgent problems in biomedical research.
156
Cooperative Research and Development Agreements and CRADA amendments to enable and extend research projects between FNL scientists and external investigators.

Our Passion is Infectious

Shape Your Career

Work with the best of the best biomedical researchers and investigators. Be a part of groundbreaking solutions that benefit public health throughout the world. And, enjoy some of the best benefits in the region. We are looking for smart, passionate problem solvers for benchwork, data science, manufacturing, and more.