A Mission to Pursue the Unsolvable

The Frederick National Laboratory is meeting the nation’s most urgent biomedical research needs and serves as a national and global resource for the scientific community. 

Cancer Research

Conference: Conference to celebrate and support Black cancer researchers 

The cancer community will come together for a two-day conference designed to celebrate Black contributions in cancer research...

Mickey Williams’ lifelong love for science enters emeritus era

Mickey Williams, Ph.D., jokes that he was “somewhat doomed to become a molecular biologist” from the very start, born within...

Specific retinoid shrinks immune checkpoint-resistant lung cancers in mice

Frederick National Laboratory researchers identified a vitamin A derivative (retinoid) that when combined with a standard...
HIV/AIDS Research

New drug to treat HIV might also be used to block infection altogether

Research led by the Frederick National Laboratory for Cancer Research (FNL) and Gilead Sciences shows the potential for a new...

Morehouse School of Medicine biospecimens to boost diversity of cancer samples for proteogenomic analysis

A national effort to understand the molecular basis of numerous cancers by analyzing proteins and genes will benefit from...
Cancer Research

AI enhances method for rapid diagnosis, potentially better treatment of endometrial cancer

Artificial intelligence has helped researchers uncover potential avenues for better treatment of endometrial cancer, the most...
What is this?

Tissue slide ablated with a Fluidigm Hyperion Imaging System that performs high-dimensional proteomics analysis of fresh-frozen tissues, tissue microarrays, smeared and formalin-fixed cells, and paraffin-embedded tissue. The Imaging Mass Cytometry Laboratory generated this image as part of their work providing cancer researchers with high-dimensional imaging analysis of tumor tissue samples at subcellular resolution.


Center for Innovation and Strategic Partnerships

We bring the Frederick National Laboratory’s distinct capabilities to the broader research community to help solve urgent problems in biomedical research.
Cooperative Research and Development Agreements and CRADA amendments to enable and extend research projects between FNL scientists and external investigators.

RAS Initiative

The RAS Initiative mobilizes the cancer research community to develop ways to treat cancers driven by the mutant RAS gene in an open model of collaboration among government, academic, and industry researchers.
People per year in the U.S. are diagnosed with cancers caused by KRAS mutations.
What is this? Surface representation of the structure of an oncogenic mutant of KRAS in complex with RAS-binding domains of RAF1 Kinase. The GMPPNP bound to oncogenic KRAS mutant is shown in ball-and-stick representation.

Our Passion is Infectious

Shape Your Career

Work with the best of the best biomedical researchers and investigators. Be a part of groundbreaking solutions that benefit public health throughout the world. And, enjoy some of the best benefits in the region. We are looking for smart, passionate problem solvers for benchwork, data science, manufacturing, and more.