A Mission to Pursue the Unsolvable

The Frederick National Laboratory is meeting the nation’s most urgent biomedical research needs and serves as a national and global resource for the scientific community. 

Symposium: 2023 Technology Showcase Highlights How Partnerships Move the Science Forward

With 100 online attendees, 180 in-person participants, 15 posters, 16 technologies, and 45 speakers, the 2023 Technology...

Public-private partnerships key to equality and equity in research

The Frederick National Laboratory’s partnerships with historically Black colleges and universities (HBCUs) came into focus at...

Long-term data paint clearer pictures of antibody levels and potency against SARS-CoV-2

After three years of COVID-19, science has learned much about the disease and the virus that causes it, SARS-CoV-2. But in...

Performance varies widely in commercial and in-house COVID-19 blood antibody tests

Many different blood tests are available for the COVID-19 virus to detect infection and to evaluate antibody responses...
HIV/AIDS Research

Case study links inflammation to HIV persistence in specific scenarios

A years-long case study has potentially identified another factor with which HIV treatment efforts must contend: Inflammation...
Cancer Research

End of NCI-MATCH trial positions precision medicine and genetic sequencing for next big push

NCI-MATCH, one of the largest cancer precision medicine clinical trials to date, closed in 2023 and its follow-on studies...
Drug Development

Faster workflows boost drug discovery in natural product-based screening

Plants, marine invertebrates, and microbes have been a major source of novel drugs against cancer, viruses, and fungal...
What is this?

Tissue slide ablated with a Fluidigm Hyperion Imaging System that performs high-dimensional proteomics analysis of fresh-frozen tissues, tissue microarrays, smeared and formalin-fixed cells, and paraffin-embedded tissue. The Imaging Mass Cytometry Laboratory generated this image as part of their work providing cancer researchers with high-dimensional imaging analysis of tumor tissue samples at subcellular resolution.


Center for Innovation and Strategic Partnerships

We bring the Frederick National Laboratory’s distinct capabilities to the broader research community to help solve urgent problems in biomedical research.
Cooperative Research and Development Agreements and CRADA amendments to enable and extend research projects between FNL scientists and external investigators.

Scientific Standards Hub

Our scientists establish standards and reference reagents for diverse scientific disciplines and encourage the adoption of benchmarks among researchers. 
disciplines with tools to help bridge gaps in scientific reproducibility.

Our Passion is Infectious

Shape Your Career

Work with the best of the best biomedical researchers and investigators. Be a part of groundbreaking solutions that benefit public health throughout the world. And, enjoy some of the best benefits in the region. We are looking for smart, passionate problem solvers for benchwork, data science, manufacturing, and more.